BGC0000465 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000465 (Xenorhabdus nematophila ATCC 19061)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	10,043	nematophin	NRP	100%

BGC0000465 - Region 1 - NRPS

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Location: 1 - 10,043 nt. (total: 10,043 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 10,044
Label		BGC0000465

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000465.1	0.67	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.34	NRP	sevadicin	Paenibacillus larvae
BGC0000396.1	0.34	NRP	nodularin	Nostoc sp. 73.1
BGC0000389.1	0.32	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.32	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000416.1	0.30	NRP	rhabdopeptide 1, rhabdopeptide 2, rhabdopeptide 3, rhabdopeptide 4	Xenorhabdus nematophila ATCC 19061
BGC0001133.1	0.29	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001434.1	0.29	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.29	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0001843.1	0.27	NRP	tridecaptin M	Paenibacillus sp. M-152

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000465.1	0.87	NRP	xenortide A, xenortide B, xenortide C, xenortide D	Xenorhabdus nematophila ATCC 19061
BGC0000426.1	0.67	NRP	sevadicin	Paenibacillus larvae
BGC0000396.1	0.67	NRP	nodularin	Nostoc sp. 73.1
BGC0000389.1	0.66	NRP	massetolide A	Pseudomonas fluorescens SS101
BGC0002071.1	0.65	NRP	Virginiafactin	Pseudomonas sp. QS1027
BGC0000416.1	0.63	NRP	rhabdopeptide 1, rhabdopeptide 2, rhabdopeptide 3, rhabdopeptide 4	Xenorhabdus nematophila ATCC 19061
BGC0001133.1	0.63	NRP	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0001434.1	0.63	NRP	nematophin	Xenorhabdus budapestensis
BGC0001698.1	0.63	NRP	nevaltophin A, nevaltophin B, nevaltophin C, nevaltophin D	Xenorhabdus budapestensis
BGC0001843.1	0.60	NRP	tridecaptin M	Paenibacillus sp. M-152

Similar known gene clusters

Module view

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NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 10043:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (NMe-phe) + (NMe-phe)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

XNC1_2299

Search NORINE for peptide: strict or relaxed

AMP-binding (554..949): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: phe, trp
Single AA prediction:: phe

Stachelhaus prediction details:

Stachelhaus sequence:: DAFTVAgVCK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 90% (moderate)

XNC1_2300

Search NORINE for peptide: strict or relaxed

AMP-binding (334..729): phe

NRPSPredictor2: phe

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: phe, trp, phg, tyr, bht
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DALlMGAVcK
Nearest Stachelhaus code:: phe
Stachelhaus code match:: 80% (moderate)