BGC0001185 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0001185 (Bacillus velezensis FZB42)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS	1	11,721	bacillibactin	NRP	38%

BGC0001185 - Region 1 - NRPS

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Location: 1 - 11,721 nt. (total: 11,721 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 11,722
Label		BGC0001185

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.93	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000401.1	0.50	NRP	paenibactin	Paenibacillus elgii B69
BGC0000309.1	0.48	NRP	bacillibactin	Bacillus subtilis subsp. subtilis str. 168
BGC0001890.1	0.36	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0000368.1	0.35	NRP	streptobactin	Streptomyces sp. ATCC 700974
BGC0002075.1	0.33	NRP, Alkaloid	Pyreudione A, Pyreudione B, Pyreudione C, Pyreudione D, Pyreudione E	Pseudomonas fluorescens
BGC0000454.1	0.29	NRP	vanchrobactin	Vibrio anguillarum RV22
BGC0001833.1	0.28	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000457.1	0.28	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001345.1	0.27	NRP	myxochelin A, myxochelin B	Stigmatella aurantiaca Sg a15

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.1	0.98	NRP	bacillibactin	Bacillus velezensis FZB42
BGC0000401.1	0.78	NRP	paenibactin	Paenibacillus elgii B69
BGC0000309.1	0.77	NRP	bacillibactin	Bacillus subtilis subsp. subtilis str. 168
BGC0001890.1	0.69	NRP	amphi-enterobactin 1, amphi-enterobactin 2, amphi-enterobactin 3, amphi-enterobactin 4	Vibrio campbellii ATCC BAA-1116
BGC0000368.1	0.68	NRP	streptobactin	Streptomyces sp. ATCC 700974
BGC0002075.1	0.66	NRP, Alkaloid	Pyreudione A, Pyreudione B, Pyreudione C, Pyreudione D, Pyreudione E	Pseudomonas fluorescens
BGC0000454.1	0.63	NRP	vanchrobactin	Vibrio anguillarum RV22
BGC0001833.1	0.62	NRP	icosalide A, icosalide B	Burkholderia gladioli
BGC0000457.1	0.61	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001345.1	0.61	NRP	myxochelin A, myxochelin B	Stigmatella aurantiaca Sg a15

Similar known gene clusters

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 11721:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

RBAM_029010

Search NORINE for peptide: strict or relaxed

AMP-binding (456..855): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

AMP-binding (1513..1929): thr

NRPSPredictor2: thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: ser, thr, dhpg, hpg
Small clusters prediction:: thr
Single AA prediction:: thr

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code:: thr
Stachelhaus code match:: 100% (strong)

RBAM_029030

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): dhb

NRPSPredictor2: dhb

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic
Large clusters prediction:: dhb, sal
Small clusters prediction:: dhb, sal
Single AA prediction:: dhb

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code:: dhb
Stachelhaus code match:: 100% (strong)