BGC0002046 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0002046 (Gynuella sunshinyii YC6258)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	transAT-PKS-like,NRPS	1	69,559

BGC0002046 - Region 1 - NRPS,transAT-PKS-like

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Location: 1 - 69,559 nt. (total: 69,559 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)
NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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Gene details

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MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

External annotation

Name		MIBiG
Version		3.0

Type		Subregion
Location		1 - 69,560
Label		BGC0002046

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002046.1	1.12	NRP, Polyketide	lobatamide A	Gynuella sunshinyii YC6258
BGC0002057.1	0.77	Polyketide	pateamine	Kiritimatiellaeota bacterium
BGC0001878.1	0.56	NRP, Polyketide	detoxin N2, detoxin N3	Streptomyces sp. NRRL B-1347
BGC0000979.1	0.53	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.53	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001479.1	0.52	NRP	anabaenopeptin NZ857, nostamide A	Nostoc punctiforme PCC 73102
BGC0001132.1	0.51	NRP	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001841.1	0.50	NRP, Polyketide	detoxin P1, detoxin P2, detoxin P3	Amycolatopsis jejuensis
BGC0000457.1	0.50	NRP	vicibactin	Rhizobium etli CFN 42
BGC0001135.1	0.49	NRP	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002046.1	0.88	NRP, Polyketide	lobatamide A	Gynuella sunshinyii YC6258
BGC0002057.1	0.72	Polyketide	pateamine	Kiritimatiellaeota bacterium
BGC0002058.1	0.66	Other	Reutericyclin A, Reutericyclin B, Reutericyclin C, Reutericyclin D	Streptococcus mutans B04Sm5
BGC0001878.1	0.63	NRP, Polyketide	detoxin N2, detoxin N3	Streptomyces sp. NRRL B-1347
BGC0001841.1	0.61	NRP, Polyketide	detoxin P1, detoxin P2, detoxin P3	Amycolatopsis jejuensis
BGC0000457.1	0.61	NRP	vicibactin	Rhizobium etli CFN 42
BGC0000145.1	0.60	Polyketide	salinosporamide A	Salinispora tropica
BGC0000979.1	0.60	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 10E9
BGC0000980.1	0.60	NRP, Polyketide	cylindrospermopsin	Aphanizomenon sp. 22D11
BGC0001041.1	0.60	NRP, Polyketide	salinosporamide A	Salinispora tropica CNB-440

Similar known gene clusters

No matches found.

Module view

Legend

NRPS/PKS products

NRPS/PKS monomers

Predicted core structure(s)

For candidate cluster 1, location 0 - 69559:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (gly - mal - mal - ohmal - mal) + (gly - ccmal - ohmal) + (Me-mal - ccmal - Me-ccmal) + (ccmal - mal - ohmal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS monomer predictions

YC6258_03641

Search NORINE for peptide: strict or relaxed

AMP-binding (866..1266): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)

YC6258_03642

Search NORINE for peptide: strict or relaxed

AMP-binding (283..681): gly

NRPSPredictor2: gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic
Large clusters prediction:: gly, ala, val, leu, ile, abu, iva
Small clusters prediction:: gly, ala
Single AA prediction:: gly

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code:: gly
Stachelhaus code match:: 100% (strong)