BGC0000517 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000517 (Halalkalibacterium halodurans C-125)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	lanthipeptide-class-ii	1	26,952	High	haloduracin β/haloduracin α	ribosomal:RiPP:Lanthipeptide

BGC0000517 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 26,952 nt. (total: 26,952 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 26,953
Label		BGC0000517

Tailoring functions

Lyases: cyclase

BH0452: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

BH0455: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000517.4	1.00	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000525.5	0.68	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0002663.2	0.58	ribosomal	amyloliquecidin GF610	Bacillus amyloliquefaciens UMAF6639
BGC0000623.3	0.54	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000500.5	0.53	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001311.5	0.52	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0001229.4	0.51	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000554.4	0.50	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000552.3	0.49	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0001391.3	0.49	ribosomal	thusin	Bacillus thuringiensis serovar rongseni

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000517.4	1.00	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000525.5	0.68	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0002663.2	0.58	ribosomal	amyloliquecidin GF610	Bacillus amyloliquefaciens UMAF6639
BGC0000623.3	0.54	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000500.5	0.53	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0001311.5	0.52	ribosomal	flavecins	Ruminococcus flavefaciens FD-1
BGC0001229.4	0.51	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0000554.4	0.50	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000552.3	0.49	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0001391.3	0.49	ribosomal	thusin	Bacillus thuringiensis serovar rongseni

Similar known clusters from MIBiG 4.0

Lanthipeptide predictions

Lanthipeptide(s) for BH0452

BH0453

Leader:

MVNSKDLRNPEFRKAQGLQFVDEVNEKELSSLAGS

Core:

GDVHAQTTWPCATVGVSVALCPTTKCTSQC

Core with dehydrations:

GDVHAQDhbDhbWPCysADhbVGVDhaVALCysPDhbDhbKCysDhbDhaQCys

antiSMASH-DB 4.0 matches for BH0453

62.5%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

GDVHAQTT--WPCATVGVSVALCPTTKCTSQC

GDV +TT P VG+SV LCPTTKCTS+C

GDVSPETTPATPTIVVGISVGLCPTTKCTSKC

60.0%

NZ_JABBGE010000004.1and 1 other:

NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13570_lanthipeptide

Lanthipeptides: HHL19_RS13570_lanthipeptide

TTWPCATVG-----VSVALCPTTKCTSQC

TTW CA V VS + CPTTKCTSQC

TTWSCAVVTAVATLVSASACPTTKCTSQC

60.0%

NZ_LMEI01000006.1and 1 other:

NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS30550_lanthipeptide

Lanthipeptides: ASC82_RS30550_lanthipeptide

TTWPCATVG-----VSVALCPTTKCTSQC

TTW CA V VS + CPTTKCTSQC

TTWSCAIVTAVATLVSASACPTTKCTSQC

with 102 more sequence matches

Only the first 10 are displayed here.

60.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS18310_lanthipeptide

TTWPCA--TVGVSVALCPTTKCTSQC

TT PC TV +SV++CPTTKCTSQC

TTLPCVGITVTISVSMCPTTKCTSQC

59.4%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

GDVHAQTT--WPCATVGVSVALCPTTKCTSQC

GDV +TT P V +SV LCPTTKCTS+C

GDVSPETTPATPTIVVAISVGLCPTTKCTSKC

58.1%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

GDVHAQTTWPCAT-VGVSVALCPTTKCTSQC

GDV+ +TT T V VS+ +CPTTKCTS+C

GDVNPETTPATPTIVAVSLGICPTTKCTSKC

56.7%

NZ_CP042598.1and 3 others:

NZ_CP042598.1 Lanthipeptides: FUT28_RS13815_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptide

Lanthipeptides: FUT28_RS13815_lanthipeptide

TTWPCATVG----VSVALCPTTKCTSQC

TTW C V S++LCPTTKCTSQC

TTWACVAVSTIVDASISLCPTTKCTSQC

56.4%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

GDVHAQTT------WPCATVGVSVA--LCPTTKCTSQC

GDV+ +TT W C T GV+V+ LCPTTKCTSQC

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

56.2%

NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

GDVHAQTTWPCATVGVSVA--LCPTTKCTSQC

GDV QTT G++V+ CPTTKCTSQC

GDVDPQTTPSSVACGIAVSALFCPTTKCTSQC

54.8%

NZ_MLKL01000042.1:

Lanthipeptides: BKK45_RS27405_lanthipeptide

GDVHAQTTWPCAT-VGVSVALCPTTKCTSQC

GDV+ +TT T V VSV LCPT CT C

GDVNPETTPATPTIVAVSVKLCPTGVCTKSC

53.3%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09875_lanthipeptide

Lanthipeptides: I4V19_RS09875_lanthipeptide

TTWPCATVG----VSVALCPTTKCTSQC

TTW C V S++LCPTTKCTS+C

TTWACVAVSTVVEASISLCPTTKCTSKC

53.1%

NZ_CP006058.1and 25 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS19790_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03330_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12920_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18410_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14705_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03575_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03180_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP063276.1 Lanthipeptides: IM743_RS02810_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03410_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03215_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03235_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10980_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15460_lanthipeptide

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

GDVHAQTT---WPCATVGVSVALCPTTKCTSQC

DV TT PC V V+ A CP+TKCTS C

ADVTPHTTPSSLPCG-VFVTAAFCPSTKCTSSC

53.1%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

GDVHAQTT--WPCATVGVSVALCPTTKCTSQC

GDV +TT P V +SV LCPT +CTS+C

GDVSPETTPATPTIVVAISVGLCPTNRCTSKC

MIBiG 4.0 matches for BH0453

37.8%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

VGVSVALCPTTKCTSQC

VGVS A CPTTKCTS+C

VGVSAAFCPTTKCTSRC

30.0%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTTKCTSQC

CPTTKCTS+C

FCPTTKCTSKC

BH0454

Leader:

MTNLLKEWKMPLERTHNNSNPAGDIFQELEDQDILAG

Core:

VNGACAWYNISCRLGNKGAYCTLTVECMPSCN

Core with dehydrations:

VNGACysAWYNIDhaCysRLGNKGAYCysDhbLDhbVECysMPDhaCysN

antiSMASH-DB 4.0 matches for BH0454

100.0%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

VNGACAWYNISCRLGNKGAYCTLTVECMPSCN

71.9%

NZ_CP006058.1and 23 others:

NZ_CP006058.1 Lanthipeptides: BAMY6639_RS13800_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP021892.1 Lanthipeptides: S100333_RS03315_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP026533.1 Lanthipeptides: C3438_RS12905_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP028961.1 Lanthipeptides: DBK22_RS18395_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP032855.1 Lanthipeptides: D9C11_RS14690_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP044132.1 Lanthipeptides: F5K02_RS03560_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP061087.1 Lanthipeptides: IAR44_RS03165_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP065791.1 Lanthipeptides: I8N73_RS03395_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP074348.1 Lanthipeptides: KHA74_RS03200_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_CP083943.1 Lanthipeptides: LCH16_RS03220_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAAHBR010000013.1 Lanthipeptides: G3T15_RS10965_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptideNZ_JAQEMJ010000013.1 Lanthipeptides: PGW53_RS15475_lanthipeptide

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

CAWY+ISC+LGNKGA+CTLTVEC SCN

CAWYDISCKLGNKGAWCTLTVECQSSCN

68.8%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

CAWY++SCRLGNKGA+CTLTVEC +CN

CAWYDVSCRLGNKGAWCTLTVECQNNCN

with 101 more sequence matches

Only the first 10 are displayed here.

62.5%

NC_021362.1and 29 others:

NC_021362.1 Lanthipeptides: BALI_RS00925_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_AP025342.1 Lanthipeptides: L6430_RS07485_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CABJBE010000012.1 Lanthipeptides: FY264_RS20080_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP010524.1 Lanthipeptides: SC10_RS00925_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP020352.1 Lanthipeptides: BLMD_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP023168.1 Lanthipeptides: CK945_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_CP118744.1 Lanthipeptides: PWG69_RS01020_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_JAHHXA010000013.1 Lanthipeptides: KM899_RS20280_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_KN125579.1 Lanthipeptides: DJ88_RS03675_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKL01000035.1 Lanthipeptides: CHCC20347_RS19035_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NIKT01000033.1 Lanthipeptides: CHCC20333_RS16145_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NILF01000041.1 Lanthipeptides: CHCC15381_RS11915_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NIMP01000010.1 Lanthipeptides: CHCC14566_RS01520_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_NKBC01000001.1 Lanthipeptides: CE036_RS00060_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptideNZ_QXII01000007.1 Lanthipeptides: D1791_RS21800_lanthipeptide

Lanthipeptides: BALI_RS00925_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C WYNISC+LGNKG +CTLT EC SC

CEWYNISCQLGNKGQWCTLTKECQRSCK

62.5%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C W+NISC LGN G +CTLT EC PSCN

CDWWNISCHLGNTGQFCTLTKECQPSCN

59.4%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C W+NISC LGN G +CTLT EC P+CN

CDWWNISCHLGNTGRFCTLTKECQPNCN

56.2%

NC_018499.1and 10 others:

NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27570_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide

Lanthipeptides: BCK_RS27860_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGNKG YCTLT ECMPSCN

LSSWLGNKGGYCTLTKECMPSCN

56.2%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C+W+N+SC LGN G YCT + ECMP+CN

CSWWNVSCHLGNDGKYCTASKECMPTCN

53.1%

NZ_CP015591.1and 19 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27560_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29375_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29370_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29365_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: IGI01_RS29005_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29780_lanthipeptideNZ_NVJC01000007.1 Lanthipeptides: COM38_RS07400_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptide

Lanthipeptides: A7A70_RS27565_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGN G YCTLT ECMPSCN

LSSWLGNNGGYCTLTKECMPSCN

53.1%

NZ_CP036019.1and 9 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27215_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_JANIOB010000033.1 Lanthipeptides: NQ113_RS28005_lanthipeptideNZ_JH791925.1 Lanthipeptides: IE3_RS28545_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20150_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20145_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26655_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26650_lanthipeptide

Lanthipeptides: EXW52_RS27215_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGNKG YCTLT ECM SCN

LSSWLGNKGGYCTLTKECMSSCN

53.1%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGN G +CTLTVECMPSCN

LSSLLGNDGKFCTLTVECMPSCN

53.1%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21835_lanthipeptide

Lanthipeptides: CN325_RS21835_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSC

C ++NISC LGN G+ CTLT EC P+C

CNFWNISCHLGNDGSVCTLTKECRPAC

50.0%

NZ_CP017762.1and 3 others:

NZ_CP017762.1 Lanthipeptides: BKP57_RS02100_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06725_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06725_lanthipeptide

Lanthipeptides: BKP57_RS02100_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C WYN+SC LGN G CT + EC CN

CPWYNLSCHLGNDGKICTFSHECTGGCN

MIBiG 4.0 matches for BH0454

87.5%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

CAWYNISCRLGNKGAYCTLTVECMPSCN

43.8%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

YNISCRLGNKGAYCTLTVECMPSCN

+++S LGN G +CTLT EC P+CN

FSLSNALGNNGGWCTLTKECQPNCN

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTVECMPSCN

CTL+ EC P+CN

CTLSKECQPNCN

allorf_00037_00159

Leader:

MPQELLAYG

Core:

TERSFLMVQRKEQQTRCLKIFTVDHLKRMNC

Core with dehydrations:

DhbERDhaFLMVQRKEQQDhbRCysLKIFDhbVDHLKRMNCys

antiSMASH-DB 4.0 matches for allorf_00037_00159

18.8%

NZ_GL732493.1:

Lanthipeptides: HMPREF0851_RS16015_lanthipeptide

RKEQQTRCLKIFTVDH

R Q RC +FT+ +

RLTMQGRCGGVFTLSY

18.4%

NZ_FOFV01000025.1:

Lanthipeptides: allorf_015764_015958_lanthipeptide

VQRKEQQTRCLKIF

+RK ++TRC K+F

TRRKPRKTRCFKVF

17.1%

NZ_JABBGB010000001.1:

Lanthipeptides: allorf_1956239_1956427_lanthipeptide

KEQQTRCLKI

+++QTRCL I

RDRQTRCLPI

allorf_00822_00935

Leader:

MERVESGYS

Core:

ITERSVPLTMTKCWRLFFIRWSLLSSLI

Core with dehydrations:

IDhbERDhaVPLDhbMDhbKCysWRLFFIRWDhaLLDhaDhaLI

antiSMASH-DB 4.0 matches for allorf_00822_00935

12.5%

NZ_CP024848.1:

Lanthipeptides: allorf_0204112_0204330_lanthipeptide

SVPLTMTKCWRL

SVP CW+L

SVPFVTLTCWKL

allorf_01155_01370

Leader:

MINRRAKMISG

Core:

KVRIKLRVDFPPCEISGVELKFFAAQRPIGIARTIDRQIPTIAIANVSSKPLSKSSPSGL

Core with dehydrations:

KVRIKLRVDFPPCysEIDhaGVELKFFAAQRPIGIARDhbIDRQIPDhbIAIANVDhaDhaKPLDhaKDhaDhaPDhaGL

allorf_03187_03369

Leader:

MANSAAA

Core:

MASRCFMPKEYSCTFRSATFVRRTSSSTSAIRDLGTFTIFRTVSRLSSPERCG

Core with dehydrations:

MADhaRCysFMPKEYDhaCysDhbFRDhaADhbFVRRDhbDhaDhaDhaDhbDhaAIRDLGDhbFDhbIFRDhbVDhaRLDhaDhaPERCysG

antiSMASH-DB 4.0 matches for allorf_03187_03369

24.5%

NZ_KV793075.1:

Lanthipeptides: allorf_044618_044788_lanthipeptide

PKEYSCTFRSATFVRRTSSSTSAIRDLGTFTIFRTVSRLSSP

PK++ C +T VR+ S+ A+R +F SR + P

PKKFGCCRPGSTLVRQHPRSSVALR----LRLFTCASRCAYP

20.8%

NZ_JACEIQ010000001.1and 1 other:

NZ_JACEIQ010000001.1 Lanthipeptides: H1191_RS00080_lanthipeptide

Lanthipeptides: H1191_RS00080_lanthipeptide

VRRTSSSTSAIRDLGTFTIFRTVSRLSSPE

V S+ T+ L TFT TVS+L +

VNAQSTGTTTKAALCTFTDCGTVSKLGGND

15.1%

NZ_AP023392.1and 4 others:

NZ_CP015557.1 Lanthipeptides: A6M16_RS04830_lanthipeptideNZ_CP065430.1 Lanthipeptides: I5V48_RS05980_lanthipeptideNZ_CP100430.1 Lanthipeptides: NLY76_RS04570_lanthipeptideNZ_JAEUXF010000003.1 Lanthipeptides: JNE40_RS02515_lanthipeptide

Lanthipeptides: H7679_RS04985_lanthipeptide

FRTVSRLSSPERCG

FRT R++S RCG

FRTAVRMTSQGRCG

MIBiG 4.0 matches for allorf_03187_03369

11.3%

BGC0000503.5 (cinA):

Lanthipeptide: cinnamycin

SCTFRSATFV

SC+F TFV

SCSFGPFTFV

allorf_03246_03401

Leader:

MLAHLRSLGA

Core:

DWLTALQQWLVAVSCPRNTLALFDLLLLLDVQAQVLQQFVI

Core with dehydrations:

DWLDhbALQQWLVAVDhaCysPRNDhbLALFDLLLLLDVQAQVLQQFVI

antiSMASH-DB 4.0 matches for allorf_03246_03401

22.0%

NZ_BMMB01000007.1:

Lanthipeptides: allorf_024907_025011_lanthipeptide

LTALQQWLVAVSCPRNTLALFDLLLLL

LTAL+ W + C FD ++L+

LTALKPWCCYIICFECGYIRFDSMMLI

17.1%

NZ_CP095740.1:

Lanthipeptides: allorf_1761125_1761268_lanthipeptide

WLTALQQWLVAVSCPRN

+L L + L ++SCPR+

FLPNLLRRLKSISCPRS

14.6%

NZ_PCGR01000003.1and 1 other:

NZ_PCGR01000003.1 Lanthipeptides: CQS04_RS09625_lanthipeptide

Lanthipeptides: CQS04_RS09625_lanthipeptide

LTALQQWLVAVSCP

+TA+ ++ A SCP

ITAITGYISANSCP

allorf_04014_04235

Leader:

MATSVIVRDYTHYFVAGKYRASKKSMEANTYPSG

Core:

TTGASLSFETVFNCNDAIVNFPFPSWLDVRNGYLFWLHK

Core with dehydrations:

DhbDhbGADhaLDhaFEDhbVFNCysNDAIVNFPFPDhaWLDVRNGYLFWLHK

antiSMASH-DB 4.0 matches for allorf_04014_04235

20.5%

NZ_FOXX01000007.1and 6 others:

NZ_LVYL01000023.1 Lanthipeptides: allorf_421773_421910_lanthipeptideNZ_LVYL01000023.1 Lanthipeptides: allorf_421773_421910_lanthipeptideNZ_LWAG01000015.1 Lanthipeptides: allorf_021388_021525_lanthipeptideNZ_LWAG01000015.1 Lanthipeptides: allorf_021388_021525_lanthipeptideNZ_LWAI01000057.1 Lanthipeptides: allorf_188984_189121_lanthipeptideNZ_LWAI01000057.1 Lanthipeptides: allorf_188984_189121_lanthipeptide

Lanthipeptides: allorf_282390_282527_lanthipeptide

TVFNCNDAIVNFPFPSWLDVRNGYL

T+F + ++PF L +NG+L

TIFKRYSVLCSYPFTKLLSFKNGHL

16.0%

NZ_KB976165.1:

Lanthipeptides: allorf_236204_236407_lanthipeptide

ASLSFETVFNCNDAIVNFPFPS

L T+ NC AI+ PS

VCLRSRTMHNCKSAILEISLPS

15.7%

NZ_KB903814.1:

Lanthipeptides: allorf_854978_855211_lanthipeptide

TTGASLSFETVFNCNDAIVNFPFPSWLDVRN

++G S+ + + +C D++ PS++ VR+

SSGHSMP-KCLSSCLDSVTPLDMPSYVKVRS

with 3 more sequence matches

14.9%

NZ_CP029354.1:

Lanthipeptides: allorf_108572_108748_lanthipeptide

CNDAIVNFPFPSWLDVR

CN+ V+ P P L R

CNEQTVHSPAPDTLAAR

11.6%

NZ_MQUS01000030.1:

Lanthipeptides: allorf_006115_006285_lanthipeptide

FPSWLDVRNGY

+PSW D G+

YPSWRDAHGGH

11.1%

NZ_CP011020.1:

Lanthipeptides: allorf_1834656_1834892_lanthipeptide

FETVFNCNDAIVNFPFPS

F + +C + +V PFPS

FTGLTSCKETLVLEPFPS

allorf_06198_06365

Leader:

MLTWRLSEEKGLRYEPFIKGRVEEAA

Core:

QRCAPCPNSPLSYPTSCDWWHGVFVFNPK

Core with dehydrations:

QRCysAPCysPNDhaPLDhaYPDhbDhaCysDWWHGVFVFNPK

antiSMASH-DB 4.0 matches for allorf_06198_06365

31.0%

NZ_CP096021.1:

Lanthipeptides: allorf_398029_398259_lanthipeptide

NSP--LSYPTSCDWW

NSP LS P++CD W

NSPRSLSVPSACDRW

27.6%

NZ_CP008953.1:

Lanthipeptides: allorf_3323853_3323972_lanthipeptide

CPNSPLSYPTS

CP SPL+YP S

CPPSPLAYPDS

27.6%

NZ_LIWC01000001.1:

Lanthipeptides: allorf_1846001_1846120_lanthipeptide

CPNSPLSYPTS

CP SPL+YP S

CPQSPLAYPDS

with 4 more sequence matches

20.7%

NZ_CP095076.1:

Lassopeptides: MUO15_RS21105_lassopeptide

NSPLSYPTSCDWW

N+P Y SCD++

NTPECYDNSCDFY

17.5%

NZ_LT607733.1:

Lanthipeptides: allorf_4401693_4401875_lanthipeptide

CPNSPLSYPTSCDWWHG

C SP + S WHG

CNRSPSAVGVSVRSWHG

17.2%

NC_019684.1:

Lassopeptides: allorf_0789291_0789491_lassopeptide

TSCDWWHGVFV

T C + HG+F

TFCKFLHGIFA

17.2%

NZ_JAQKZU010000014.1:

Lanthipeptides: allorf_35422_35553_lanthipeptide

CDWWHGVFVFN

C W+ +FVF

CSWYKKLFVFK

allorf_07549_07683

Leader:

MATIVVPLGSPDLRNDPIHEQCLFA

Core:

TCLLRSLFHPYHFVVLFND

Core with dehydrations:

DhbCysLLRDhaLFHPYHFVVLFND

allorf_20791_20967

Leader:

MWILHDVGNGKHSRAETDRNVQEKGKSQGRFLSPSQSHGS

Core:

DNSGARATNARDESSCLC

Core with dehydrations:

DNDhaGARADhbNARDEDhaDhaCysLCys

allorf_21150_21284

Leader:

MLPSLPSSPFIGSICSSSSKDRHDTYCIKMRKEKAISGS

Core:

RFISC

Core with dehydrations:

RFIDhaCys

allorf_21436_21663

Leader:

MTPLHFRSSPFSSIVRHALSYEFLRGIMTDSHKVGMKRRTSLISPNDIDHIPNVKGSENQAFIFS

Core:

DRVACSREDE

Core with dehydrations:

DRVACysDhaREDE

Lanthipeptide(s) for BH0455

BH0453

Leader:

MVNSKDLRNPEFRKAQGLQFVDEVNEKELSSLAGS

Core:

GDVHAQTTWPCATVGVSVALCPTTKCTSQC

Core with dehydrations:

GDVHAQDhbDhbWPCysADhbVGVDhaVALCysPDhbDhbKCysDhbDhaQCys

antiSMASH-DB 4.0 matches for BH0453

62.5%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

GDVHAQTT--WPCATVGVSVALCPTTKCTSQC

GDV +TT P VG+SV LCPTTKCTS+C

GDVSPETTPATPTIVVGISVGLCPTTKCTSKC

60.0%

NZ_JABBGE010000004.1and 1 other:

NZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13570_lanthipeptide

Lanthipeptides: HHL19_RS13570_lanthipeptide

TTWPCATVG-----VSVALCPTTKCTSQC

TTW CA V VS + CPTTKCTSQC

TTWSCAVVTAVATLVSASACPTTKCTSQC

60.0%

NZ_LMEI01000006.1and 1 other:

NZ_LMEI01000006.1 Lanthipeptides: ASC82_RS30550_lanthipeptide

Lanthipeptides: ASC82_RS30550_lanthipeptide

TTWPCATVG-----VSVALCPTTKCTSQC

TTW CA V VS + CPTTKCTSQC

TTWSCAIVTAVATLVSASACPTTKCTSQC

with 102 more sequence matches

Only the first 10 are displayed here.

60.0%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS18310_lanthipeptide

TTWPCA--TVGVSVALCPTTKCTSQC

TT PC TV +SV++CPTTKCTSQC

TTLPCVGITVTISVSMCPTTKCTSQC

59.4%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

GDVHAQTT--WPCATVGVSVALCPTTKCTSQC

GDV +TT P V +SV LCPTTKCTS+C

GDVSPETTPATPTIVVAISVGLCPTTKCTSKC

58.1%

NC_018499.1and 5 others:

Lanthipeptides: BCK_RS27845_lanthipeptide

GDVHAQTTWPCAT-VGVSVALCPTTKCTSQC

GDV+ +TT T V VS+ +CPTTKCTS+C

GDVNPETTPATPTIVAVSLGICPTTKCTSKC

56.7%

NZ_CP042598.1and 3 others:

NZ_CP042598.1 Lanthipeptides: FUT28_RS13815_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptideNZ_RKNR01000012.1 Lanthipeptides: EGW35_RS11625_lanthipeptide

Lanthipeptides: FUT28_RS13815_lanthipeptide

TTWPCATVG----VSVALCPTTKCTSQC

TTW C V S++LCPTTKCTSQC

TTWACVAVSTIVDASISLCPTTKCTSQC

56.4%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

GDVHAQTT------WPCATVGVSVA--LCPTTKCTSQC

GDV+ +TT W C T GV+V+ LCPTTKCTSQC

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

56.2%

NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

GDVHAQTTWPCATVGVSVA--LCPTTKCTSQC

GDV QTT G++V+ CPTTKCTSQC

GDVDPQTTPSSVACGIAVSALFCPTTKCTSQC

54.8%

NZ_MLKL01000042.1:

Lanthipeptides: BKK45_RS27405_lanthipeptide

GDVHAQTTWPCAT-VGVSVALCPTTKCTSQC

GDV+ +TT T V VSV LCPT CT C

GDVNPETTPATPTIVAVSVKLCPTGVCTKSC

53.3%

NZ_JADPDT010000005.1and 1 other:

NZ_JADPDT010000005.1 Lanthipeptides: I4V19_RS09875_lanthipeptide

Lanthipeptides: I4V19_RS09875_lanthipeptide

TTWPCATVG----VSVALCPTTKCTSQC

TTW C V S++LCPTTKCTS+C

TTWACVAVSTVVEASISLCPTTKCTSKC

53.1%

NZ_CP006058.1and 25 others:

Lanthipeptides: BAMY6639_RS19790_lanthipeptide

GDVHAQTT---WPCATVGVSVALCPTTKCTSQC

DV TT PC V V+ A CP+TKCTS C

ADVTPHTTPSSLPCG-VFVTAAFCPSTKCTSSC

53.1%

NZ_CP036019.1and 7 others:

Lanthipeptides: EXW52_RS27190_lanthipeptide

GDVHAQTT--WPCATVGVSVALCPTTKCTSQC

GDV +TT P V +SV LCPT +CTS+C

GDVSPETTPATPTIVVAISVGLCPTNRCTSKC

MIBiG 4.0 matches for BH0453

37.8%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

VGVSVALCPTTKCTSQC

VGVS A CPTTKCTS+C

VGVSAAFCPTTKCTSRC

30.0%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

LCPTTKCTSQC

CPTTKCTS+C

FCPTTKCTSKC

BH0454

Leader:

MTNLLKEWKMPLERTHNNSNPAGDIFQELEDQDILAG

Core:

VNGACAWYNISCRLGNKGAYCTLTVECMPSCN

Core with dehydrations:

VNGACysAWYNIDhaCysRLGNKGAYCysDhbLDhbVECysMPDhaCysN

antiSMASH-DB 4.0 matches for BH0454

100.0%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

VNGACAWYNISCRLGNKGAYCTLTVECMPSCN

71.9%

NZ_CP006058.1and 23 others:

Lanthipeptides: BAMY6639_RS13800_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

CAWY+ISC+LGNKGA+CTLTVEC SCN

CAWYDISCKLGNKGAWCTLTVECQSSCN

68.8%

NZ_CP063276.1and 1 other:

NZ_CP063276.1 Lanthipeptides: IM743_RS02795_lanthipeptide

Lanthipeptides: IM743_RS02795_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

CAWY++SCRLGNKGA+CTLTVEC +CN

CAWYDVSCRLGNKGAWCTLTVECQNNCN

with 101 more sequence matches

Only the first 10 are displayed here.

62.5%

NC_021362.1and 29 others:

Lanthipeptides: BALI_RS00925_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C WYNISC+LGNKG +CTLT EC SC

CEWYNISCQLGNKGQWCTLTKECQRSCK

62.5%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06310_lanthipeptide

Lanthipeptides: EG886_RS06310_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C W+NISC LGN G +CTLT EC PSCN

CDWWNISCHLGNTGQFCTLTKECQPSCN

59.4%

NZ_CP034118.1and 1 other:

NZ_CP034118.1 Lanthipeptides: EG886_RS06305_lanthipeptide

Lanthipeptides: EG886_RS06305_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C W+NISC LGN G +CTLT EC P+CN

CDWWNISCHLGNTGRFCTLTKECQPNCN

56.2%

NC_018499.1and 10 others:

Lanthipeptides: BCK_RS27860_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGNKG YCTLT ECMPSCN

LSSWLGNKGGYCTLTKECMPSCN

56.2%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21845_lanthipeptide

Lanthipeptides: CN325_RS21845_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C+W+N+SC LGN G YCT + ECMP+CN

CSWWNVSCHLGNDGKYCTASKECMPTCN

53.1%

NZ_CP015591.1and 19 others:

Lanthipeptides: A7A70_RS27565_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGN G YCTLT ECMPSCN

LSSWLGNNGGYCTLTKECMPSCN

53.1%

NZ_CP036019.1and 9 others:

Lanthipeptides: EXW52_RS27215_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGNKG YCTLT ECM SCN

LSSWLGNKGGYCTLTKECMSSCN

53.1%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

ISCRLGNKGAYCTLTVECMPSCN

+S LGN G +CTLTVECMPSCN

LSSLLGNDGKFCTLTVECMPSCN

53.1%

NZ_NTSF01000026.1and 1 other:

NZ_NTSF01000026.1 Lanthipeptides: CN325_RS21835_lanthipeptide

Lanthipeptides: CN325_RS21835_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSC

C ++NISC LGN G+ CTLT EC P+C

CNFWNISCHLGNDGSVCTLTKECRPAC

50.0%

NZ_CP017762.1and 3 others:

NZ_CP017762.1 Lanthipeptides: BKP57_RS02100_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06725_lanthipeptideNZ_CP073011.1 Lanthipeptides: KBP50_RS06725_lanthipeptide

Lanthipeptides: BKP57_RS02100_lanthipeptide

CAWYNISCRLGNKGAYCTLTVECMPSCN

C WYN+SC LGN G CT + EC CN

CPWYNLSCHLGNDGKICTFSHECTGGCN

MIBiG 4.0 matches for BH0454

87.5%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

CAWYNISCRLGNKGAYCTLTVECMPSCN

43.8%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

YNISCRLGNKGAYCTLTVECMPSCN

+++S LGN G +CTLT EC P+CN

FSLSNALGNNGGWCTLTKECQPNCN

20.5%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

CTLTVECMPSCN

CTL+ EC P+CN

CTLSKECQPNCN

allorf_04014_04235

Leader:

MATSVIVRDYTHYFVAGKYRASKKSMEANTYPSG

Core:

TTGASLSFETVFNCNDAIVNFPFPSWLDVRNGYLFWLHK

Core with dehydrations:

DhbDhbGADhaLDhaFEDhbVFNCysNDAIVNFPFPDhaWLDVRNGYLFWLHK

antiSMASH-DB 4.0 matches for allorf_04014_04235

20.5%

NZ_FOXX01000007.1and 6 others:

Lanthipeptides: allorf_282390_282527_lanthipeptide

TVFNCNDAIVNFPFPSWLDVRNGYL

T+F + ++PF L +NG+L

TIFKRYSVLCSYPFTKLLSFKNGHL

16.0%

NZ_KB976165.1:

Lanthipeptides: allorf_236204_236407_lanthipeptide

ASLSFETVFNCNDAIVNFPFPS

L T+ NC AI+ PS

VCLRSRTMHNCKSAILEISLPS

15.7%

NZ_KB903814.1:

Lanthipeptides: allorf_854978_855211_lanthipeptide

TTGASLSFETVFNCNDAIVNFPFPSWLDVRN

++G S+ + + +C D++ PS++ VR+

SSGHSMP-KCLSSCLDSVTPLDMPSYVKVRS

with 3 more sequence matches

14.9%

NZ_CP029354.1:

Lanthipeptides: allorf_108572_108748_lanthipeptide

CNDAIVNFPFPSWLDVR

CN+ V+ P P L R

CNEQTVHSPAPDTLAAR

11.6%

NZ_MQUS01000030.1:

Lanthipeptides: allorf_006115_006285_lanthipeptide

FPSWLDVRNGY

+PSW D G+

YPSWRDAHGGH

11.1%

NZ_CP011020.1:

Lanthipeptides: allorf_1834656_1834892_lanthipeptide

FETVFNCNDAIVNFPFPS

F + +C + +V PFPS

FTGLTSCKETLVLEPFPS

allorf_06198_06365

Leader:

MLTWRLSEEKGLRYEPFIKGRVEEAA

Core:

QRCAPCPNSPLSYPTSCDWWHGVFVFNPK

Core with dehydrations:

QRCysAPCysPNDhaPLDhaYPDhbDhaCysDWWHGVFVFNPK

antiSMASH-DB 4.0 matches for allorf_06198_06365

31.0%

NZ_CP096021.1:

Lanthipeptides: allorf_398029_398259_lanthipeptide

NSP--LSYPTSCDWW

NSP LS P++CD W

NSPRSLSVPSACDRW

27.6%

NZ_CP008953.1:

Lanthipeptides: allorf_3323853_3323972_lanthipeptide

CPNSPLSYPTS

CP SPL+YP S

CPPSPLAYPDS

27.6%

NZ_LIWC01000001.1:

Lanthipeptides: allorf_1846001_1846120_lanthipeptide

CPNSPLSYPTS

CP SPL+YP S

CPQSPLAYPDS

with 4 more sequence matches

20.7%

NZ_CP095076.1:

Lassopeptides: MUO15_RS21105_lassopeptide

NSPLSYPTSCDWW

N+P Y SCD++

NTPECYDNSCDFY

17.5%

NZ_LT607733.1:

Lanthipeptides: allorf_4401693_4401875_lanthipeptide

CPNSPLSYPTSCDWWHG

C SP + S WHG

CNRSPSAVGVSVRSWHG

17.2%

NC_019684.1:

Lassopeptides: allorf_0789291_0789491_lassopeptide

TSCDWWHGVFV

T C + HG+F

TFCKFLHGIFA

17.2%

NZ_JAQKZU010000014.1:

Lanthipeptides: allorf_35422_35553_lanthipeptide

CDWWHGVFVFN

C W+ +FVF

CSWYKKLFVFK

allorf_07549_07683

Leader:

MATIVVPLGSPDLRNDPIHEQCLFA

Core:

TCLLRSLFHPYHFVVLFND

Core with dehydrations:

DhbCysLLRDhaLFHPYHFVVLFND

allorf_20791_20967

Leader:

MWILHDVGNGKHSRAETDRNVQEKGKSQGRFLSPSQSHGS

Core:

DNSGARATNARDESSCLC

Core with dehydrations:

DNDhaGARADhbNARDEDhaDhaCysLCys

allorf_21150_21284

Leader:

MLPSLPSSPFIGSICSSSSKDRHDTYCIKMRKEKAISGS

Core:

RFISC

Core with dehydrations:

RFIDhaCys

allorf_21436_21663

Leader:

MTPLHFRSSPFSSIVRHALSYEFLRGIMTDSHKVGMKRRTSLISPNDIDHIPNVKGSENQAFIFS

Core:

DRVACSREDE

Core with dehydrations:

DRVACysDhaREDE

allorf_23547_23642

Leader:

MRWGCELPKACHLKKLLILSNSLMS

Core:

TVLWNC

Core with dehydrations:

DhbVLWNCys

allorf_24370_24459

Leader:

MSSSTFPSTSFAA

Core:

RTACSPGFVSRQHEQH

Core with dehydrations:

RDhbACysDhaPGFVDhaRQHEQH

antiSMASH-DB 4.0 matches for allorf_24370_24459

33.3%

NZ_CP031447.1:

Lanthipeptides: allorf_0151829_0151969_lanthipeptide

RTACSPGFVSRQHE

R C PG VSR H+

RPTCGPGPVSRSHD

23.1%

NZ_SIMU01000019.1:

Lanthipeptides: allorf_19974_20192_lanthipeptide

TACSPGFVSRQHEQ

T C PG R E+

TPCPPGSAVRPQER

11.1%

NZ_AP022615.1:

Lanthipeptides: allorf_3179492_3179677_lanthipeptide

CSPGFVSRQH

C+P + +RQH

CNPSWCNRQH

allorf_24373_24495

Leader:

MLLMLSAYKAGGTGSTSCERSRRECRRRHGG

Core:

SVSWARLNC

Core with dehydrations:

DhaVDhaWARLNCys

antiSMASH-DB 4.0 matches for allorf_24373_24495

31.2%

NZ_CP041767.1:

Lanthipeptides: FO446_RS14760_lanthipeptide

SVSWARLNC

SV+W + NC

SVTWCQSNC

MIBiG 4.0 matches for allorf_24373_24495

7.1%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

SWARLNC

+W ++C

AWYNISC

allorf_25228_25392

Leader:

MDSRNSCMLGS

Core:

SCIVKNASIMSSRKSSGRSILIACGPFGIGSDSAITFNCSKFG

Core with dehydrations:

DhaCysIVKNADhaIMDhaDhaRKDhaDhaGRDhaILIACysGPFGIGDhaDDhaAIDhbFNCysDhaKFG

antiSMASH-DB 4.0 matches for allorf_25228_25392

24.4%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27200_lanthipeptide

Lanthipeptides: EXW52_RS27200_lanthipeptide

RKSSGRSILIACGPFGIGSDSAITFNC

+KSSG CG +DS+ T+NC

KKSSG------CGRCEPRNDSSYTYNC

20.9%

NZ_CP040916.1:

Lanthipeptides: allorf_9186874_9187053_lanthipeptide

IACG---PFGIGSDSA

IACG P G+G D+A

IACGRRGPDGVGHDTA

16.3%

NZ_CP027862.1and 1 other:

NZ_CP027862.1 Lanthipeptides: allorf_0109701_0109913_lanthipeptide

Lanthipeptides: allorf_0109701_0109913_lanthipeptide

GPFGIGSDSAITFNCSKFG

GP G D F+C + G

GPTGPVQDPLAPFDCRQPG

allorf_25821_25913

Leader:

MLRGKIFVTREEKNYG

Core:

KCDGKSVWCFNIIT

Core with dehydrations:

KCysDGKDhaVWCysFNIIDhb

antiSMASH-DB 4.0 matches for allorf_25821_25913

7.7%

NZ_RAII01000001.1:

Lanthipeptides: allorf_2955953_2956186_lanthipeptide

DGKSVWC

DG + WC

DGHTAWC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

BH0453 - Class II

Cleavage pHMM score: 1.00

RODEO score: 0

Monoisotopic mass: 2919.4 Da

Molecular weight: 2921.3 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 2939.3 Da N = 1; 2957.4 Da N = 2; 2975.4 Da N = 3; 2993.4 Da N = 4

BH0454 - Class II

Cleavage pHMM score: 0.40

RODEO score: 0

Monoisotopic mass: 3368.5 Da

Molecular weight: 3370.9 Da

Number of bridges: 4

allorf_04014_04235 - Class II

Cleavage pHMM score: -6.70

RODEO score: 0

Monoisotopic mass: 4397.2 Da

Molecular weight: 4399.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4417.9 Da N = 1; 4436.0 Da N = 2; 4454.0 Da N = 3; 4472.0 Da N = 4; 4490.0 Da N = 5

allorf_06198_06365 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 3263.5 Da

Molecular weight: 3265.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3283.7 Da N = 1

allorf_07549_07683 - Class II

Cleavage pHMM score: -5.30

RODEO score: 0

Monoisotopic mass: 2284.2 Da

Molecular weight: 2285.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2303.7 Da N = 1

allorf_20791_20967 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1796.8 Da

Molecular weight: 1797.9 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 1815.9 Da N = 1; 1833.9 Da N = 2

allorf_21150_21284 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 606.3 Da

Molecular weight: 606.7 Da

Number of bridges: 1

allorf_21436_21663 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1160.5 Da

Molecular weight: 1161.2 Da

Number of bridges: 1

allorf_23547_23642 - Class II

Cleavage pHMM score: -6.90

RODEO score: 0

Monoisotopic mass: 716.3 Da

Molecular weight: 716.8 Da

Number of bridges: 1

allorf_24370_24459 - Class II

Cleavage pHMM score: -6.20

RODEO score: 0

Monoisotopic mass: 1784.9 Da

Molecular weight: 1785.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1803.9 Da N = 1; 1822.0 Da N = 2

allorf_24373_24495 - Class II

Cleavage pHMM score: -5.90

RODEO score: 0

Monoisotopic mass: 998.5 Da

Molecular weight: 999.1 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 1017.2 Da N = 1

allorf_25228_25392 - Class II

Cleavage pHMM score: -6.70

RODEO score: 0

Monoisotopic mass: 4198.2 Da

Molecular weight: 4200.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 4218.9 Da N = 1; 4236.9 Da N = 2; 4254.9 Da N = 3; 4272.9 Da N = 4; 4290.9 Da N = 5; 4309.0 Da N = 6; 4327.0 Da N = 7; 4345.0 Da N = 8

allorf_25821_25913 - Class II

Cleavage pHMM score: -6.30

RODEO score: 0

Monoisotopic mass: 1576.8 Da

Molecular weight: 1577.9 Da

Number of bridges: 2

BH0453 - Class II

Cleavage pHMM score: 1.00

RODEO score: 0

Monoisotopic mass: 2919.4 Da

Molecular weight: 2921.3 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 2939.3 Da N = 1; 2957.4 Da N = 2; 2975.4 Da N = 3; 2993.4 Da N = 4

BH0454 - Class II

Cleavage pHMM score: 0.40

RODEO score: 0

Monoisotopic mass: 3368.5 Da

Molecular weight: 3370.9 Da

Number of bridges: 4

allorf_00037_00159 - Class II

Cleavage pHMM score: -7.10

RODEO score: 0

Monoisotopic mass: 3766.0 Da

Molecular weight: 3768.4 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3786.5 Da N = 1; 3804.5 Da N = 2

allorf_00822_00935 - Class II

Cleavage pHMM score: -4.80

RODEO score: 0

Monoisotopic mass: 3269.9 Da

Molecular weight: 3272.0 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 3290.0 Da N = 1; 3308.0 Da N = 2; 3326.0 Da N = 3; 3344.0 Da N = 4; 3362.1 Da N = 5; 3380.1 Da N = 6

allorf_01155_01370 - Class II

Cleavage pHMM score: -6.70

RODEO score: 0

Monoisotopic mass: 6352.7 Da

Molecular weight: 6356.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 6374.5 Da N = 1; 6392.5 Da N = 2; 6410.5 Da N = 3; 6428.5 Da N = 4; 6446.6 Da N = 5; 6464.6 Da N = 6; 6482.6 Da N = 7; 6500.6 Da N = 8

allorf_03187_03369 - Class II

Cleavage pHMM score: -6.40

RODEO score: 0

Monoisotopic mass: 5680.9 Da

Molecular weight: 5684.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 5702.5 Da N = 1; 5720.5 Da N = 2; 5738.5 Da N = 3; 5756.6 Da N = 4; 5774.6 Da N = 5; 5792.6 Da N = 6; 5810.6 Da N = 7; 5828.6 Da N = 8; 5846.7 Da N = 9; 5864.7 Da N = 10; 5882.7 Da N = 11; 5900.7 Da N = 12; 5918.7 Da N = 13; 5936.8 Da N = 14

allorf_03246_03401 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 4639.6 Da

Molecular weight: 4642.4 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4660.5 Da N = 1; 4678.5 Da N = 2

allorf_04014_04235 - Class II

Cleavage pHMM score: -6.70

RODEO score: 0

Monoisotopic mass: 4397.2 Da

Molecular weight: 4399.9 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4417.9 Da N = 1; 4436.0 Da N = 2; 4454.0 Da N = 3; 4472.0 Da N = 4; 4490.0 Da N = 5

allorf_06198_06365 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 3263.5 Da

Molecular weight: 3265.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3283.7 Da N = 1

allorf_07549_07683 - Class II

Cleavage pHMM score: -5.30

RODEO score: 0

Monoisotopic mass: 2284.2 Da

Molecular weight: 2285.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 2303.7 Da N = 1

allorf_20791_20967 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1796.8 Da

Molecular weight: 1797.9 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 1815.9 Da N = 1; 1833.9 Da N = 2

allorf_21150_21284 - Class II

Cleavage pHMM score: -6.00

RODEO score: 0

Monoisotopic mass: 606.3 Da

Molecular weight: 606.7 Da

Number of bridges: 1

allorf_21436_21663 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 1160.5 Da

Molecular weight: 1161.2 Da

Number of bridges: 1